Eating Disorders: An Intensive DBT Program for Patients With Multidiagnostic Eating Disorder Presentations: A Case Series Analysis.

An intensive DBT program for patients with multidiagnostic eating disorder presentations: A case series analysis.

Filed under: Eating Disorders

Int J Eat Disord. 2013 Feb 5;
Federici A, Wisniewski L

OBJECTIVE: This study presents case-series data on a novel outpatient program that blends dialectical behavior therapy (DBT) with standard eating disorder (ED) interventions (i.e., food exposure, weight monitoring, cognitive modification, ED psychoeducation) for patients with complex and multidiagnostic ED presentations. METHOD: Quantitative and qualitative data was collected on a sample of seven consecutively admitted women who presented with a severe ED, a history of several failed treatment attempts, pervasive emotion dysregulation, and significant Axis I or II psychiatric comorbidity (e.g., PTSD, borderline personality disorder). RESULTS: Treatment was associated with reductions in ED symptoms, suicidal and self-injurious behaviors, treatment interfering behaviors, psychiatric and medical hospitalizations, and clinican burnout. DISCUSSION: Overall, the results suggest that this blended DBT/cognitive behavior therapy for ED treatment model is a promising intervention for this complex and “hard to treat” population. © 2013 by Wiley Periodicals, Inc. (Int J Eat Disord 2013).
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Factors associated with chronic gastritis in patients with presence and absence of Helicobacter pylori.

Filed under: Eating Disorders

Arq Bras Cir Dig. 2012 Jun; 25(2): 96-100
Ddine LC, Ddine CC, Rodrigues CC, Kirsten VR, Colpo E

BACKGROUND – Chronic gastritis is an inflammation of the stomach mucosa, which is considered its main etiological factor the Helicobacter pylori. AIM – To observe the differences in patients with chronic gastritis as well as the presence and absence of H. pylori, to obtain a better understanding of the etiological factors, clinical, dietary and lifestyle habits and associated diseases. METHODS – This was a descriptive study, retrospective medical records of patients with chronic gastritis treated as outpatients. Endoscopy and research of H. pylori was used in the diagnosis of chronic gastritis. The survey was conducted through a questionnaire to ascertain the risk factors for chronic gastritis and the clinical manifestations of disease, dietary and lifestyle habits, family history of the disease, weight changes and medications. For statistical analysis was used Spearman coefficient. Data were considered statistically significant p<0.05. RESULTS - Of the 94 patients evaluated were symptomatic with heartburn, belching, epigastric pain, fullness and nausea. In 56.6% (n = 54) of individuals was detected the presence of bacteria and in 43.6% (n = 40) was not found any specific etiologic factor. Was performed chi-square statistical test of clinical manifestations and factors such as stress and anxiety, leading to positive correlation. It became evident that the risk factors for disease are diverse, including the use of drugs, alcoholism, eating quickly, talking during meals, with significant relation to abdominal distension and reflux. The patients with the bacteria, had a higher risk of experiencing these symptoms. CONCLUSION - Various etiological factors in eating habits and lifestyle, as smoking, alcoholism, anxiety, stress, associated diseases and inadequate nutrition, interact to the onset of clinical manifestations, and the presence and absence of H. pylori did not show significant changes in patient clinical status. HubMed – eating


Steroids hormones and BDNF.

Filed under: Eating Disorders

Neuroscience. 2013 Feb 1;
Pluchino N, Russo M, Santoro AN, Litta P, Cela V, Genazzani AR

Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin abundantly expressed in several areas of CNS and known to induce a lasting potentiation of synaptic efficacy, to enhance specific learning and memory processes. BDNF is one of the key molecules modulating brain plasticity and it affects cognitive deficit associated with aging and neurodegenerative disease. Several studies have shown an altered BDNF production and secretion in a variety of neurodegenerative diseases like Alzheimer’s and Parkinson’s diseases but also in mood disorders like depression, eating disorders and schizophrenia. Plasma BDNF is also a biomarker of impaired memory and general cognitive function in ageing women. Gonadal steroids are involved in the regulation of several CNS processes, specifically mood, affective and cognitive functions during fertile life and reproductive aging. These observations lead many scientists to investigate a putative co-regulation between BDNF and gonadal and/or adrenal steroids and their relationship with gender difference in the incidence of mental diseases. This overview aims to summarize the current knowledge on the correlation between BDNF expression/function and both gonadal (progesterone, estrogens, testosterone) and adrenal hormones (mainly cortisol and DHEA) with relevance for clinical application.
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Are restrained eaters accurate monitors of their intoxication? Results from a field experiment.

Filed under: Eating Disorders

Addict Behav. 2012 Dec 22; 38(4): 1966-1969
Buchholz LJ, Crowther JH, Olds RS, Smith KE, Ridolfi DR

Brief interventions encourage college students to eat more before drinking to prevent harm (Dimeff et al., 1999), although many women decrease their caloric intake (Giles et al., 2009) and the number of eating episodes (Luce et al., 2012) prior to drinking alcohol. Participants were 37 undergraduate women (24.3% Caucasian) who were recruited from a local bar district in the Midwest. This study examined whether changes in eating after intending to drink interacted with dietary restraint to predict accuracy of one’s intoxication. Results indicated that changes in eating significantly moderated the relationship between dietary restraint and accuracy of one’s intoxication level. After eating more food before intending to drink, women higher in restraint were more likely to overestimate their intoxication than women lower in restraint. There were no differences between women with high levels and low levels of dietary restraint in the accuracy of their intoxication after eating less food before intending to drink. Future research would benefit from examining interoceptive awareness as a possible mechanism involved in this relationship.
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