Depression Treatment: The Relationship Between Disability, Quality of Life and Fear-Avoidance Beliefs in Patients With Chronic Low Back Pain.

The relationship between disability, quality of life and fear-avoidance beliefs in patients with chronic low back pain.

Filed under: Depression Treatment

Turk Neurosurg. 2012; 22(6): 724-31
Guclu DG, Guclu O, Ozaner A, Senormanci O, Konkan R

The aim of this study is to investigate the relationship between fear and avoidance beliefs with the disability of patients with chronic low back pain and the prediction of quality of life. MATERIAL and105 outpatients with chronic low back pain were included in the study. Patients were evaluated with a sociodemographic questionnaire Visual Analog Scale Roland Morris Disability Questionnaire Beck anxiety inventory Beck depression inventory, Somatosensory Amplification Scale Fear and avoidance beliefs questionaire and Short form-36 health survey questionnaire.As pain intensity increased, FABQ increased. Higher levels of anxiety, depression, FABQ (work) leads to higher level of disability. The disability predictors were found to be pain intensity and level of anxiety. When levels of pain intensity, level of anxiety and depression, FABQ increased, physical function decreased. Pain intensity and FABQ (physical) were found to be the predictors of quality of life.Findings of our study were compatible with the previous studies that evaluated the relationship between pain intensity and FAB with the disability of patients with chronic low back pain. We think that it’d have a role for the perception of disability and connected to this to prevent the impairment of life quality by implications for FAB in these patients.
HubMed – depression


Is it social support or depression that plays a role in survival of breast carcinoma?

Filed under: Depression Treatment

Psychooncology. 2012 Dec; 21(12): 1367
Willers I, Vermuë S, Mols F, Husson O

HubMed – depression


Morphometric analysis of vascular pathology in the orbitofrontal cortex of older subjects with major depression.

Filed under: Depression Treatment

Int J Geriatr Psychiatry. 2012 Dec 3;
Miguel-Hidalgo JJ, Jiang W, Konick L, Overholser JC, Jurjus GJ, Stockmeier CA, Steffens DC, Krishnan KR, Rajkowska G

OBJECTIVE: Late-life depression has been associated with risk for cerebrovascular pathology, as demonstrated in neuroimaging studies of older depressed patients, as well as mood disorder following cerebrovascular accidents. However, more research is needed on neuroanatomical changes in late-life depression, where there has been no clearly documented link to brain injury. Such studies should examine morphological changes in medium and small sized vessels that supply the cortical gray and white matter. METHODS: The present study used a non-specific histological Nissl staining and a more vessel-specific immunolabeling with endothelial marker von Willebrand Factor (vWF) to estimate density and size of blood vessel segments in the orbitofrontal cortex of 16 older subjects with major depressive disorder (MDD) and 9 non-psychiatric comparison subjects. RESULTS: The density of Nissl-stained vessel segments and of segments with perivascular spaces was higher in subjects with MDD than in comparison subjects in gray (GM) and white matter (WM). In GM, the density of vWF-immunoreactive segments with cross-sectional areas greater than 800?µm(2) was higher in MDD. In WM, only the density of vWF-immunoreactive segments with patent perivascular spaces and diameters larger than 60?µm was higher in subjects with MDD. Also in the WM, only subjects with late-onset MDD presented a significantly higher density of vWF-positive segments than comparison subjects. CONCLUSIONS: In older subjects with MDD, there appear to be morphological changes that increase visibility of medium-sized vessel segments with some labeling techniques, and this increased visibility may be related to increased patency of perivascular spaces around arterioles. Copyright © 2012 John Wiley & Sons, Ltd.
HubMed – depression


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