Depression Treatment: Mental Health Spillovers and the Millennium Development Goals: The Case of Perinatal Depression in Khayelitsha, South Africa.

Mental health spillovers and the Millennium Development Goals: The case of perinatal depression in Khayelitsha, South Africa.

Filed under: Depression Treatment

J Glob Health. 2012 Jun; 2(1): 10302
Tsai AC, Tomlinson M

HubMed – depression


Massive colchicine overdose with recovery.

Filed under: Depression Treatment

Case Rep Nephrol Urol. 2012 Jan; 2(1): 20-4
Iosfina I, Lan J, Chin C, Werb R, Levin A

Colchicine is an active alkaloid that is commonly used for treatment of multiple diseases including gout, primary biliary cirrhosis and familial Mediterranean fever. Less commonly, it has been implicated in several fatal overdoses. Deaths from colchicine overdoses are usually due to multi-organ failure, whether directly from colchicine toxicity or due to ensuing sepsis. We report an extreme case of colchicine ingestion (1.38 mg/kg), which is the largest reported non-fatal colchicine overdose. The patient was a 47-year-old First Nations woman with a history of depression and no other comorbidities. Ingestion was intentional and initial presentation was within 2 h of ingestion, at which point she had normal clinical and laboratory parameters. Early implementation of a targeted therapeutic strategy directed at the predicted multi-organ failure which included aggressive use of a GI decontamination protocol, timely supportive measures including ventilator support and renal replacement therapy, as well as the utilization of broad-spectrum antibiotics and G-CSF for sepsis and leucopenia management, resulted in successful support and discharge of this patient off dialysis.
HubMed – depression


The Quality of Life and Depressive Mood among Korean Patients with Hand Eczema.

Filed under: Depression Treatment

Ann Dermatol. 2012 Nov; 24(4): 430-7
Yu M, Han TY, Lee JH, Son SJ

Hand eczema is a disease frequently observed in dermatological practice. This condition has negative emotional, social, and psychological effects due to its impact on daily life and morphological appearance. Due to its considerable effect on the quality of life, this disease can lead to depression. However, not many studies have been performed on the quality of life and depression in hand eczema patients.The purpose of this study is to investigate the association between the quality of life, depression, and disease severity in hand eczema patients in South Korea.A total of 138 patients with hand eczema participated in this study. The patients’ quality of life was assessed by a self-administered questionnaire using the Dermatology Life Quality Index (DLQI). Data on patients suffering from depression was obtained using the Beck’s Depression Inventory (BDI-II). The disease severity was determined during the clinical examination, according to the Hand Eczema Severity Index (HECSI).We found positive associations between DLQI and HECSI scores (p<0.05). BDI-II scores had also statistically positive correlations with HECSI scores (p<0.05). DLQI and BDI-II scores both increased with disease severity.Hand eczema negatively affected the quality of life and mood of patients relative to the disease severity. Therefore, we suggest that quality of life modification and emotional support should be included as a part of treatment for hand eczema. HubMed – depression


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