Depression Treatment: Factors Associated With Developmental Concern and Intent to Access Therapy Following Discharge From the NICU.

Factors Associated With Developmental Concern and Intent to Access Therapy Following Discharge From the NICU.

Filed under: Depression Treatment

Pediatr Phys Ther. 2013; 25(1): 62-9
Pineda RG, Castellano A, Rogers C, Neil JJ, Inder T

: To determine factors associated with mothers’ concern about infant development and intent to access therapy services following neonatal intensive care unit (NICU) discharge.: Infant medical factors, magnetic resonance imaging results, neurobehavior at term, maternal factors, and maternal perceptions about developmental concern and intent to access therapy at NICU discharge were prospectively collected in 84 infants born premature (<30 weeks gestation). Regression was used to determine factors associated with developmental concern and intent to access therapy at NICU discharge.: Decreased developmental concern was reported by mothers with more children (P = .007). Infant stress signs (P = .038), higher maternal education (P = .047), reading books (P = .030), and maternal depression (P = .018) were associated with increased developmental concern. More maternal education was associated with more intent to access services (P = .040). Conclusion: Maternal factors, rather than infant factors, had important associations with caregiver concern. In contrast, abnormal term neurobehavior and/or the presence of cerebral injury were not associated with caregiver concern about development. HubMed – depression


Mental disorders in primary care in Israel: prevalence and risk factors.

Filed under: Depression Treatment

Soc Psychiatry Psychiatr Epidemiol. 2013 Jan 4;
Laufer N, Zilber N, Jecsmien P, Maoz B, Grupper D, Hermesh H, Gilad R, Weizman A, Munitz H

OBJECTIVE: Psychiatric morbidity is common among patients in primary care services and leads to disability and increased use of medical services. Comparison of primary care and community prevalence data is of interest in relation to the health services planning for mental disorders. The aim of the present study was to measure prevalence of mental disorders in six primary care clinics in Israel and to assess risk factors for these disorders. METHOD: Prevalence of mental disorders was measured in a sample of 2,948 primary care consecutive attendees, using two-stage stratified sampling with the General Health Questionnaire 12 (GHQ-12) and the Composite International Diagnostic Interview (CIDI). RESULTS: A high rate (46.3 %) of current mental disorders was found, with rates of current depressive episode, generalized anxiety disorder, somatization disorder, and neurasthenia being relatively high in comparison with rates in other countries. Low education was a risk factor for all categories of disorders, unemployment a risk factor for depressive disorders, and parenthood was protective for most categories of disorders. CONCLUSIONS: High rates of mental disorders were found in this Israeli primary care sample as compared to other countries, while in the community the rates were midrange as compared to other countries, pointing to a relatively higher use of primary care services by patients with mental disorders in Israel than in other countries.
HubMed – depression


Arabinoxylan rice bran (MGN-3/Biobran) provides protection against whole-body ?-irradiation in mice via restoration of hematopoietic tissues.

Filed under: Depression Treatment

J Radiat Res. 2013 Jan 3;
Ghoneum M, Badr El-Din NK, Abdel Fattah SM, Tolentino L

The aim of the current study is to examine the protective effect of MGN-3 on overall maintenance of hematopoietic tissue after ?-irradiation. MGN-3 is an arabinoxylan from rice bran that has been shown to be a powerful antioxidant and immune modulator. Swiss albino mice were treated with MGN-3 prior to irradiation and continued to receive MGN-3 for 1 or 4 weeks. Results were compared with mice that received radiation (5 Gy ? rays) only, MGN-3 (40 mg/kg) only and control mice (receiving neither radiation nor MGN-3). At 1 and 4 weeks post-irradiation, different hematological, histopathological and biochemical parameters were examined. Mice exposed to irradiation alone showed significant depression in their complete blood count (CBC) except for neutrophilia. Additionally, histopathological studies showed hypocellularity of their bone marrow, as well as a remarkable decrease in splenic weight/relative size and in number of megakaryocytes. In contrast, pre-treatment with MGN-3 resulted in protection against irradiation-induced damage to the CBC parameters associated with complete bone marrow cellularity, as well as protection of the aforementioned splenic changes. Furthermore, MGN-3 exerted antioxidative activity in whole-body irradiated mice, and provided protection from irradiation-induced loss of body and organ weight. In conclusion, MGN-3 has the potential to protect progenitor cells in the bone marrow, which suggests the possible use of MGN-3/Biobran as an adjuvant treatment to counteract the severe adverse side effects associated with radiation therapy.
HubMed – depression


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