Collaborative Care for Sick-Listed Workers With Major Depressive Disorder: A Randomised Controlled Trial From the Netherlands Depression Initiative Aimed at Return to Work and Depressive Symptoms.

Collaborative care for sick-listed workers with major depressive disorder: a randomised controlled trial from the Netherlands Depression Initiative aimed at return to work and depressive symptoms.

Filed under: Addiction Rehab

Occup Environ Med. 2012 Oct 30;
Vlasveld MC, van der Feltz-Cornelis CM, Adèr HJ, Anema JR, Hoedeman R, van Mechelen W, Beekman AT

OBJECTIVES: Major depressive disorder (MDD) is associated with absenteeism. In this study, the effectiveness of collaborative care, with a focus on return to work (RTW), was evaluated in its effect on depressive symptoms and the duration until RTW in sick-listed workers with MDD in the occupational health setting. METHODS: In this randomised controlled trial, 126 sick-listed workers with MDD were randomised to usual care (N=61) or collaborative care (N=65). Collaborative care was applied by the occupational physician care manager, supported by a web-based tracking system and a consultant psychiatrist. Primary outcome measure was time to response. Secondary outcome measures were time to remission, depressive symptoms as continuous measure and the duration until full RTW. RESULTS: Collaborative care participants had a shorter time to response, with a difference of 2.8 months. However, no difference was found on time to remission or depressive symptoms as continuous measure. With a mean of 190 days in the collaborative care group, and 210 days in the usual care group, the groups did not differ significantly from each other in the duration until full RTW. Adherence to the collaborative care intervention was low. CONCLUSIONS: These results do not justify a widespread implementation of collaborative care in occupational healthcare, as it was operationalised in this study. However, since the study might have been underpowered for RTW and because treatment integrity was low, further research, with larger sample sizes, is needed to develop the best fitting (collaborative care) model for addressing RTW in depressed sick-listed workers. TRIAL REGISTRATION:: ISRCTN78462860.
HubMed – addiction


Estimation of BDNF gene polymorphism and predisposition to dependence development for selected psychoactive compounds: Genetic aspects of addiction with the selected drugs, amphetamine, tetrahydrocannabinol and opiates.

Filed under: Addiction Rehab

Hum Exp Toxicol. 2012 Oct 30;
Biskupska J, Borowiak K, Karlin-Grazewicz K, Janus T, Waloszczyk P, Potocka-Banas B, Machoy-Mokrzynska A, Ossowski A, Ciechanowicz A

The etiology of drug addiction, a central nervous system (CNS) disease, is not fully known. This complex problem is believed to be connected with concurrently affecting genetic, psychological and environmental factors. The development of addiction is connected with CNS reinforcement system and dopaminergic neurotransmission. Molecular processes are postulated to be of universal character and allow to presume a similar mechanism of dependence for both ethanol and other substances. Therefore, elements of dopaminergic transmission become excellent candidates for the examination of genetic influence on the development of addiction. A relationship between alcoholic disease and the presence of TaqIA1 and DRD2 alleles permits to initiate another investigation of gene-coding DRD2 dopamine receptor. The latest results indicate the importance of brain-derived neurotrophic factor (BDNF) in the regulation of dopaminergic route. The purpose of this research was to reveal the relationship between the Val66Met BDNF gene polymorphism and dependence of psychoactive agent. The examinations were performed with the Local Research Ethics Committee approval and patient’s consent. The study group consisted of 100 patients (88 men and 12 women) aged 18-52 years, qualified for research program according to the International Classification of Diseases, Tenth Revision (ICD-10) requirements, medical examination and detailed questionnaire.
HubMed – addiction


A perspective on the future public health: an integrative and ecological framework.

Filed under: Addiction Rehab

Perspect Public Health. 2012 Nov; 132(6): 313-9
Hanlon P, Carlisle S, Hannah M, Lyon A, Reilly D

Modernity has brought health and social benefits to many societies, not least through the insights of science and technology. Yet, modernity has also been associated with a number of cultural characteristics, such as materialism, individualism, consumerism and an addiction to continuing economic growth, that seem potentially harmful to health and well-being and inimical to social equity. There is an emerging body of evidence that suggests that, in the affluent world, some of our most intractable contemporary health problems are, in fact, the product of modernity. This suggests that the tools of modernity (its science and its technology) are ill suited to finding solutions. This poses a problem for public health, as this discipline is itself a product of modernity and thus appears ill equipped to deal with the conditions and challenges of a rapidly changing and unstable world, one where the very sustainability of human society is now in question. This paper argues that a new paradigm for the future public health is needed. It presents an integrative, ecological framework as a starting point from which public health might grasp the opportunities for change inherent in the ‘modern’ threats we face. It suggests a number of features that will need to underpin such a paradigm shift in thinking and practice. However, as this paper is written from the perspective of an affluent, developed society (albeit from a perspective that is explicitly critical of the goals, trends and values that seem to characterise such societies), other voices from other places need to be heard. We hope that others will want to engage with our arguments and suggestions, whether to challenge and refute these, or to further their development.
HubMed – addiction



Bradford Health Services – Drug Addiction – Recovery Moments While the path to drug addiction begins with the voluntary act of taking drugs, in time,with repeated use, many people lose the ability to choose. The addicted person can become focused on seeking and consuming drugs to the exclusion of everything else. Addiction is a brain disease that affects the brain in many ways, including reward and motivation, learning and memory, and inhibitory control over behavior. Drug abuse and addiction can disrupt many aspects of an individual’s life. Effective treatment programs use various components to address a particular aspect of the illness and its consequences. Addiction treatment and 12-Step Programs can help individuals stop using drugs, maintain a drug-free lifestyle, and improve social and behavior interactions in the family, at work, and in society. Addiction is a chronic disease and generally people cannot simply stop using drugs for a few days and be magically cured. Most patients require sustained therapy or long-term care to achieve recovery. Thank you for watching this short video and taking the first step to build a solid foundation to recovery. A foundation built on knowledge, love and compassion. We want you, your family and friends to live a life free from addiction. A life full of Hope. Help is out there. Don’t miss the opportunity to reach out for help. Be prepared with the knowledge and a plan to change a life in an amazing and positive way. Click the link below to watch our other videos and learn


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