Association Between Serotonin Transporter Gene Polymorphism and Eating Disorders Outcome: A 6-Year Follow-Up Study.

Association between serotonin transporter gene polymorphism and eating disorders outcome: A 6-year follow-up study.

Filed under: Eating Disorders

Am J Med Genet B Neuropsychiatr Genet. 2012 Apr 9;
Castellini G, Ricca V, Lelli L, Bagnoli S, Lucenteforte E, Faravelli C, Sorbi S, Nacmias B

Eating disorder patients show different long-term outcomes, and trait-related alterations of serotonergic function, which might be related with the serotonin transporter (5-HTT) gene. We studied the relationships between 5-HTTLPR polymorphism, eating specific and general psychopathology and the long-term outcome of anorexia nervosa (AN) and bulimia nervosa (BN) patients. We evaluated the distribution of the functional 5-HTTLPR polymorphism in a series of 201 Italian, Caucasian, eating disorder patients (113 with AN and 88 with BN binge/purging (BP subtype) and in 150 Caucasian unrelated controls. Prior to starting an individual cognitive behavior therapy, a clinical assessment was performed by means of the structured clinical interview for DSM-IV axis I disorders and several self-report questionnaires. This assessment was repeated at the end of treatment, 3 years after the end of treatment and 3 years after the first follow-up. Diagnostic changes between AN and BN were frequent (28.3%), and the presence of depressive disorders was associated with a higher rate of diagnostic crossover during the follow-up period. The S-allele of the 5-HTTLPR genotype increases the risk susceptibility for both depressive comorbidity (OR?=?4.23; 95% CI, 1.45-12.37) and diagnostic crossover during the follow-up period in AN patients (OR?=?5.04; 95% CI, 1.69-14.98). Logistic regression analyses confirmed these findings, when the interaction between genotype and psychiatric comorbidity as predictors of diagnostic instability in AN patients were taken into account. No significant association was found between 5-HTTLPR genotype and recovery. The S-allele of the 5-HTTLPR genotype increases the risk for depressive disorders comorbidity, and moderates the long-term outcome of anorectic patients. © 2012 Wiley Periodicals, Inc.
HubMed – eating

 

Evaluation of a Cognitive Remediation Therapy Group for Adolescents with Anorexia Nervosa: Pilot Study.

Filed under: Eating Disorders

Eur Eat Disord Rev. 2012 Apr 4;
Pretorius N, Dimmer M, Power E, Eisler I, Simic M, Tchanturia K

OBJECTIVE: Cognitive remediation therapy (CRT) has been used with adults with anorexia nervosa (AN) in individual and group formats; however, evaluation of CRT with adolescents in this population is very limited. METHOD: Seven CRT groups were carried out with a total of 30 adolescents with AN. Adolescents’ cognitive flexibility and motivation was assessed before and after the group, and they completed qualitative questionnaires after the group to determine their perceptions. RESULTS: There was a small effect size in self-reported cognitive flexibility post group. Adolescents found the group interesting and useful; however, some wanted more support with application to real life. DISCUSSION: Cognitive remediation therapy has the potential to be used with adolescents with AN. More research is needed to determine if CRT is beneficial for young people with AN. Copyright © 2012 John Wiley & Sons, Ltd and Eating Disorders Association.
HubMed – eating

 

The Impact of Self-Reported Pubertal Status and Pubertal Timing on Disordered Eating in Irish Adolescents.

Filed under: Eating Disorders

Eur Eat Disord Rev. 2012 Apr 4;
McNicholas F, Dooley B, McNamara N, Lennon R

This paper considers the impact of pubertal status and pubertal timing on disordered eating in Irish adolescents. 1190 boys and 1841 girls completed the Eating Attitudes Test-26, the Eating Disorder Inventory-III and self-report measures of pubertal status and pubertal timing. Regarding pubertal status, greater maturity in girls was associated with increased overall eating concerns, higher drive for thinness and higher levels of body dissatisfaction. In boys, greater maturity was associated with lower drive for thinness and lower body dissatisfaction. Regarding pubertal timing, early-maturing girls showed the most eating concerns, the highest drive for thinness, scored highest on bulimic symptoms and were the most dissatisfied with their bodies. In contrast, late-maturing boys had more bulimic symptoms and more dissatisfaction with their bodies than on-time peers. The findings suggest that puberty itself is a risk factor for disordered eating for girls rather than boys; however, pubertal timing is a risk factor for both. Copyright © 2012 John Wiley & Sons, Ltd and Eating Disorders Association.
HubMed – eating

 


 

The Truth About Eating Disorders: Anorexia – Produced By: Magdalene John Anorexia is probably the most well known eating disorder. But what is it? And how does it effect people’s lives and their faith? Watch as Magdalene John explains this complex disorder. FEATURED IN REPORT: Emily Wierenga-Battled with Anorexia Nervosa www.emilywierenga.com Trent Wierenga was Anorexic Patti Perry-RN, MSN Nurse, Psychotherapist www.eatingdisorders.ca Erin Baan-Battled with Anorexia Nervosa

 

Brain activity gives scientists clues about eating disorders

Filed under: Eating Disorders

Dawn Turner Trice Bio | E-mail | Recent columns The goal is to use information about brain activity patterns to help tailor treatments for people with eating disorders. But the information can also be used for healthier people who simply want to …
Read more on Chicago Tribune

 

Summer Heats Up Eating Disorder Warning Signs

Filed under: Eating Disorders

For teenage girls burdened by body-image concerns, swimsuit season can awaken eating disorder behaviors that may have hibernated or gone unnoticed during the colder months. Dr. Judy Scheel, Ph.D., author of When Food is Family: A Loving Approach to …
Read more on openPR (press release)

 

Facebook may amplify eating disorders and poor body image

Filed under: Eating Disorders

A new study of Facebook users finds that using the social networking site may lead to poor body image and low self esteem, amplifying eating disorders: A majority are more conscious of body and weight. By Stephanie Hanes, Correspondent / March 30, …
Read more on Christian Science Monitor

 

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