An Oncology Mind-Body Medicine Day Care Clinic: Concept and Case Presentation.

An Oncology Mind-Body Medicine Day Care Clinic: Concept and Case Presentation.

Filed under: Depression Treatment

Integr Cancer Ther. 2013 Jan 16;
Paul A, Cramer H, Lauche R, Altner N, Langhorst J, Dobos GJ

Introduction. Cancer diagnosis and treatment are often associated with physical and psychosocial impairments. Many cancer patients request complementary and alternative therapies such as mind-body medicine. Concept. The department of internal and integrative medicine at the Essen-Mitte Clinics offer a mind-body medicine day care clinic for cancer patients that is based on the Mindfulness-Based Stress Reduction Program and the mind-body medicine cancer program of the Harvard Mind/Body Medical Institute. The program encompasses mindfulness training, yoga, mindful exercise, nutrition, naturopathic self-help strategies, and cognitive restructuring. Cases. Two patients who had participated in the day care clinic program are presented here. One patient presented with anxiety and depression after recently diagnosed breast cancer and the other with psychological impairments as a result of multiple nevi excision after malignant melanoma surgery. Both patients improved in terms of anxiety and further psychological symptoms. CONCLUSIONS: The Essen-Mitte Clinics mind-body medicine day care clinic appears to alleviate psychological consequences of cancer and its treatment. Further studies and randomized controlled trials are necessary to confirm these results.
HubMed – depression

 

Role of serotonin in seasonal affective disorder.

Filed under: Depression Treatment

Eur Rev Med Pharmacol Sci. 2013 Jan; 17(1): 49-55
Gupta A, Sharma PK, Garg VK, Singh AK, Mondal SC

This review was prepared with an aim to show role of serotonin in seasonal affective disorder. Seasonal affective disorder, which is also called as winter depression or winter blues, is mood disorder in which persons with normal mental health throughout most of the year will show depressive symptoms in the winter or, less commonly, in the summer. Serotonin is an important endogenous neurotransmitter which also acts as neuromodulator. The least invasive, natural, and researched treatment of seasonal affective disorder is natural or otherwise is light therapy. Negative air ionization, which acts by liberating charged particles on the sleep environment, has also become effective in treatment of seasonal affective disorder.  
HubMed – depression

 

Biochemical mechanism studies of venlafaxine by metabonomic method in rat model of depression.

Filed under: Depression Treatment

Eur Rev Med Pharmacol Sci. 2013 Jan; 17(1): 41-8
Fenli S, Feng W, Ronghua Z, Huande L

Venlafaxine is a new antidepressant that has a chemical structure and neuropharmacologic profile distinct from those of existing antidepressants. The studies about the mechanism of pharmacological action of venlafaxine mostly investigated the effects of venlafaxine on 5-hydroxytryptamine (5-HT), norepinephrine (NE) and dopamine (DA) levels, while only few studies examined the effects on the metabolites levels and ratio of these monoamines neurotransmitters.To study the biochemical mechanism of venlafaxine through determining the metabolism of monoamine neurotransmitters in brain tissues of rat model of depression after administration of venlafaxine using metabonomic method.The rat model of depression was established by using the methods of separation and chronic unpredictable stress. We have determined 5-HT, NE, DA and their metabolites, i.e., 5-hydroxyindole-3-acetic acid (5-HIAA), 4-hydroxy-3-methoxyphenylglycol (MHPG) sulfate, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in rat brain tissues by liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) following chronic administration of different venlafaxine doses (8, 16, 32 mg·kg-1) and saline solution for 14 days. Linear discriminant analysis (LDA) and principal components analysis (PCA) were used in data analysis of metabonomic.Compared with saline, venlafaxine could significantly increase brain 5-HT and NE levels at middle dose (16 mg·kg-1) or high dose (32 mg·kg-1), especially at middle dose. These increases were greater than those seen with the comparable dose of selective serotonin reuptake inhibitor (SSRI), fluoxetine, under the same experimental conditions.Venlafaxine lowers brain neurotransmitter metabolite levels by decreasing brain neurotransmitters turnover. Venlafaxine could correct the disorder of neurotransmitters’ metabolism and coordinate the balance of 5-HT, NE and DA to reach the anti-depressed function.
HubMed – depression

 

Treatment of Depression in Adolescents and Adults, Paperback by Springer, Dav...

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Chronic Depression: Diagnosis & Treatment for Dysthymic Disorder by Anthony Wilk
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Cognitive-Behavioral Treatment of Depression
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