Aims, Design and Methods of a Case-Control Study for the Assessment of the Role of Dietary Habits, Eating Behaviors and Environmental Factors, on the Development of Breast Cancer.

Aims, design and methods of a case-control study for the assessment of the role of dietary habits, eating behaviors and environmental factors, on the development of breast cancer.

Filed under: Eating Disorders

Maturitas. 2012 Nov 3;
Mourouti N, Papavagelis C, Psaltopoulou T, Aravantinos G, Samantas E, Filopoulos E, Manousou A, Plytzanopoulou P, Vassilakou T, Malamos N, Panagiotakos DB

In this work the aims, methodology and procedures of a case-control study that was developed for assessing the role of dietary habits, eating behaviors and environmental factors on the development of breast cancer, is presented. During 2010-2012, 250 consecutive women patients, newly diagnosed with breast cancer and 250 population-based, healthy subjects (controls) age-matched to the cases, were enrolled. Socio-demographic, dietary, psychological, lifestyle as well as environmental characteristics (i.e., exposure to pollution, pesticides, electromagnetic fields and radon) were recorded through face-to-face interviews with the participants. Dietary habits and eating behaviors were evaluated with a special questionnaire that had been developed for the study, and was found relatively valid and reliable.
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Lipid metabolism and oxidative stress in children after liver transplantation treated with sirolimus.

Filed under: Eating Disorders

Pediatr Transplant. 2012 Dec; 16(8): 901-6
Jankowska I, Czubkowski P, Socha P, Wierzbicka A, Teisseyre M, Teisseyre J, Paw?owska J

Lipid disturbances are one of the most frequent side effects of SRL; however, clinical consequences are not known. The aim of the study was to evaluate the risk of AS in children after LTx treated with SRL. In 17 children with median age 13.2 yr (1.9-17.9) who received SRL on average for 4.1 yr (s.d. ± 2.9) we measured and compared with age-matched healthy control group (n = 45) lipid parameters and markers of AS: ADMA, oxyLDL, GSH, GPx, TC, TG, HDL cholesterol, LDL cholesterol, VLDL cholesterol, ApoAI, ApoB, ApoE, lipoprotein (a) (Lp(a)). We found no major differences in cholesterol, cholesterol in lipoprotein fractions and TG concentrations between patients receiving SRL and the control group. ApoE was markedly increased in the study group (19.1 g/L [±1.8]) when compared to controls (9.8 [±3.9]). ApoA1 was decreased in the study group: 1.30 g/L (±0.2) vs. 1.45 (±0.25), p = 0.04. ApoB and Lpa concentrations were similar in both groups. There were differences in oxidative stress markers: GSH 743 (±66.2) mol/mL vs. 780 (±48.2), p = 0.02 and GPx 32.8 (±5.5) U/gHb vs. 34.3(±2.6), p = 0.01. Markers of AS: ADMA did not differ between groups and oxidized LDLc was significantly lower in SRL group: 190 mU/mL (±113) vs. 237 (±107) in control, p < 0.05. SRL does not significantly disturb lipid metabolism and oxidative status in children after LTx. HubMed – eating


Quetiapine-induced sleep-related eating disorder-like behavior: a case series.

Filed under: Eating Disorders

J Med Case Rep. 2012 Nov 6; 6(1): 380
Tamanna S, Ullah MI, Pope CR, Holloman G, Koch CA

ABSTRACT: INTRODUCTION: Somnambulism or sleepwalking is a disorder of arousal from non-rapid eye movement sleep. The prevalence of sleep-related eating disorder has been found to be approximately between 1% and 5% among adults. Many cases of medication-related somnambulism and sleep-related eating disorder-like behavior have been reported in the literature. Quetiapine, an atypical antipsychotic medication, has been associated with somnambulism but has not yet been reported to be associated with sleep-related eating disorder. CASE PRESENTATION: Case 1 is a 51-year-old obese African American male veteran with a body mass index of 34.11kg/m2 and severe sleep apnea who has taken 150mg of quetiapine at bedtime for more than one year for depression. He developed sleepwalking three to four nights per week which resolved after stopping quetiapine while being compliant with bi-level positive pressure ventilation therapy. At one year follow-up, his body mass index was 32.57kg/m2.Case 2 is a 50-year-old African American female veteran with a body mass index of 30.5kg/m2 and mild sleep apnea who has taken 200mg of quetiapine daily for more than one year for depression. She was witnessed to sleepwalk three nights per week which resolved after discontinuing quetiapine while being treated with continuous positive airway pressure. At three months follow-up, her body mass index was 29.1kg/m2. CONCLUSION: These cases illustrate that quetiapine may precipitate complex motor behavior including sleep-related eating disorder and somnambulism in susceptible patients. Atypical antipsychotics are commonly used in psychiatric and primary care practice, which means the population at risk of developing parasomnia may often go unrecognized. It is important to recognize this potential adverse effect of quetiapine and, to prevent injury and worsening obesity, discuss this with the patients who are prescribed these medications.
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Self-care behaviours of chemotherapy patients.

Filed under: Eating Disorders

J Med Assoc Thai. 2012 Jun; 95 Suppl 6: S30-7
Prutipinyo C, Maikeow K, Sirichotiratana N

To present study self-care behaviours and variables associated with self-care behaviors of cancer patients treated with chemotherapy.This is a descriptive, cross-sectional study in cancer patients receiving chemotherapy in out-patient department of the National Regional Cancer Center in Chonburi City. Interview questionnaire was the data collection instrument for 133 purposive sampling.Survey result indicated that patients were highly aware of the support provided by staff on service supports, emotional supports and informational support. The present study results also found that the top 3 patient self-care knowledge are, avoiding those who have cold when the patients have low white blood cells, eating hot (cooked well with heat) food and knowing the effects of chemotherapy on causing low red blood cells, lowplatelets and low white blood cells. The top 3 self-care behaviours of the patients were, always eat cooked food, inquire and understand the instructions from health personnel for self-care and always check herself/himself to maintain good health. However patients did not usually exercise at least 15 minutes every day, select the recreational activities adequately, and not finding ways to improve their own health. Results from hypothesis testing, indicated that only knowledge variable was associated with self-care behaviours of patients treated with chemotherapy. The demographic variables such as age, marital status, education level, income were not associated with self-care behaviours of patients treated with chemotherapyKnowledge is associated with self-care behaviours of cancer patients who received chemotherapy. Providing health promotion for patients is necessary for them to have better self-care behaviours.
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