Addiction Rehab: Challenges of Recognition of the Psychiatric Aspects of Intimate Partner Violence.

Challenges of recognition of the psychiatric aspects of intimate partner violence.

Filed under: Addiction Rehab

Ann Med Health Sci Res. 2012 Jan; 2(1): 78-86
Achor J, Ibekwe P

Even though intimate partner violence represents a major public health problem in Nigeria, much of its associated burden of psychiatric morbidity presenting in the clinical setting goes unrecognized and untreated.The purpose of this paper is to clarify the psychiatric perspectives on intimate partner violence and highlight the barriers that militate against the detection of these problems in clinical contexts.This paper utilized the framework of relevant case series and a focused review of the relevant literature to describe and annotate the psychiatric problems of the victims and perpetrators of intimate partner violence in southeast Nigeria.The major barriers to detection of the psychiatric disorders occurring in the context of intimate partner violence include patients’ feelings of shame, reticence about the abuse experiences in the clinical encounter, and cloaking of their emotional distress in somatic complaints. Also, the poor interviewing skills of many doctors and their difficulty in processing psychosocial matters contributes to the non-detection of psychiatric problems occurring in the context of partner violence.Concerted efforts directed towards the improved detection, treatment and/or referral of patients presenting with these difficulties will enhance their wellbeing and quality of life.
HubMed – addiction


TBK1 Kinase Addiction in Lung Cancer Cells Is Mediated via Autophagy of Tax1bp1/Ndp52 and Non-Canonical NF-?B Signalling.

Filed under: Addiction Rehab

PLoS One. 2012; 7(11): e50672
Newman AC, Scholefield CL, Kemp AJ, Newman M, McIver EG, Kamal A, Wilkinson S

K-Ras dependent non-small cell lung cancer (NSCLC) cells are ‘addicted’ to basal autophagy that reprograms cellular metabolism in a lysosomal-sensitive manner. Here we demonstrate that the xenophagy-associated kinase TBK1 drives basal autophagy, consistent with its known requirement in K-Ras-dependent NSCLC proliferation. Furthermore, basal autophagy in this context is characterised by sequestration of the xenophagy cargo receptor Ndp52 and its paralogue Tax1bp1, which we demonstrate here to be a bona fide cargo receptor. Autophagy of these cargo receptors promotes non-canonical NF-?B signalling. We propose that this TBK1-dependent mechanism for NF-?B signalling contributes to autophagy addiction in K-Ras driven NSCLC.
HubMed – addiction


Interactions between Affective and Cognitive Processing Systems in Problematic Gamblers: A Functional Connectivity Study.

Filed under: Addiction Rehab

PLoS One. 2012; 7(11): e49923
van Holst RJ, van der Meer JN, McLaren DG, van den Brink W, Veltman DJ, Goudriaan AE

Motivational and cognitive abnormalities are frequently reported in pathological gambling. However, studies simultaneously investigating motivational and cognitive processing in problematic gamblers are lacking, limiting our understanding of the interplay between these systems in problematic gambling. Studies in non-clinical samples indicate that interactions between dorsal “executive” and ventral “affective” processing systems are necessary for adequate responses in various emotive situations.We conducted a generalized Psycho-Physiological Interaction (gPPI) analysis to assess the influence of affective stimuli on changes in functional connectivity associated with response inhibition in 16 treatment seeking problematic gamblers (PRGs) and 15 healthy controls (HCs) using an affective Go-NoGo fMRI paradigm including neutral, gambling-related, positive and negative pictures as neutral and affective conditions.Across groups, task performance accuracy during neutral inhibition trials was positively correlated with functional connectivity between the left caudate and the right middle frontal cortex. During inhibition in the gambling condition, only in PRGs accuracy of task performance was positively correlated with functional connectivity within sub-regions of the dorsal executive system. Group interactions showed that during neutral inhibition, HCs exhibited greater functional connectivity between the left caudate and occipital cortex than PRGs. In contrast, during inhibition in the positive condition, PRGs compared to HCs showed greater functional connectivity between the left caudate and occipital cortex. During inhibition trials in the negative condition, a stronger functional connectivity between the left caudate and the right anterior cingulate cortex in PRGs compared to HCs was present. There were no group interactions during inhibition in the gambling condition.During gamble inhibition PRGs seem to benefit more from functional connectivity within the dorsal executive system than HCs, because task accuracy in this condition in PRGs is positively correlated with functional connectivity, although the groups show similar connectivity patterns during gamble inhibition. Greater functional connectivity between the ventral affective system and the dorsal executive system in PRGs in the affective conditions compared to HCs, suggests facilitation of the dorsal executive system when affective stimuli are present specifically in PRGs.
HubMed – addiction


Working With the Suicidal Client Who Also Abuses Substances.

Filed under: Addiction Rehab

Cogn Behav Pract. 2012 May; 19(2): 245-255
Esposito-Smythers C, Walsh A, Spirito A, Rizzo C, Goldston DB, Kaminer Y

Substance use disorders and suicidal thoughts and behaviors commonly co-occur in adolescent and adult psychiatric populations and are often functionally interrelated. Although the evidence base for treatment of this population is sparse, integrated cognitive behavioral treatment (CBT) protocols, or those that rely heavily on CBT techniques, hold promise. In this paper, we provide an overview of the evidence-based literature for interventions that target suicidal behavior and substance use disorders with adults and adolescents. We then discuss the manner in which these behaviors may be functionally interrelated and offer a conceptual framework (S-O-R-C) to guide case conceptualization and treatment planning for clients with co-occurring suicidality and substance use disorders. Next, we provide a case example of a client with suicidal behavior and an alcohol use disorder and demonstrate how to apply an integrated CBT treatment protocol to this case. This case example is followed by a more general discussion about the potential advantages of integrated CBT protocols for suicidality and substance use disorders, guidelines for prioritizing treatment targets and skill selection for each individual client, and other important treatment considerations. We conclude with recommendations for future research in this area.
HubMed – addiction



Bradford Health Services – Continuing Care Program – Recovery Moments The goal of aftercare and continuing care is to provide support and encouragement to a person in the recovery process, following initial treatment for alcoholism or drug addiction. continuing care programs help individuals remain free from alcohol or drug use or abuse through relapse-prevention education and information. Aftercare is the stage following more intensive services and is meant to help achieve and maintain recovery. Aftercare is conducted in a group setting with a facilitator leading the group. Group participants discuss issues relating to maintaining their sobriety. Continuing care participants are encouraged to attend 12-Step Programs as art of their aftercare. Many programs also offer a family continuing care group for family members. Thank you for watching this short video and taking the first step to build a solid foundation to recovery. A foundation built on knowledge, love and compassion. We want you, your family and friends to live a life free from addiction. A life full of Hope. Help is out there. Don’t miss the opportunity to reach out for help. Be prepared with the knowledge and a plan to change a life in an amazing and positive way. For immediate help call Bradford Health Services 888.577.0012 Twitter Facebook Pinterest Other Videos and Resources Bradford Website http


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